CQI Partner PCAB Accredited

Sterile Compounding

Sterile Compounding

We prepare sterile compounding products including injections, ophthalmics and medications complying with USP specifications such as USP Chapter 797.

 

sterile

Injectables

Examples of sterile injections that can be compounded by prescription order include:

  • Intracavernosal injections of papaverine and phentolamine, sometimes with prostaglandin E1 (“tri-mix”) in customized doses*
  • 17-alpha-hydroxyprogesterone caproate (17P)*
  • Riboflavin
  • Vitamin B-12 injections (Methylcobalamin injections)
  • Diagnostic preparations (i.e., methylene blue)
  • Intravenous glutathione

*see more info below

Ask us about combinations to meet specific needs or medications that are currently unavailable or have been discontinued for non-safety reasons (such as when a newer therapy reduces the need and therefore decreased use results in the medication no longer being profitable to manufacturer).

Intracavernosal injections

Intracavernosal injection of drugs such as papaverine, phentolamine, and prostaglandin E1 is an effective treatment for patients with erectile dysfunction (ED).

Clin Cornerstone. 2005;7(1):37-45.
Available and future treatments for erectile dysfunction.
Royal Victoria Hospital, Belfast, UK.
Click here to access the PubMed abstract of this article.

Treatment with self-injections of vasoactive drugs in diabetic men with severe ED is a safe and effective long term treatment. A key for successful maintenance therapy is the adjustment of the dosage to optimal levels for satisfactory erections.

Asian J Androl. 2006 Mar;8(2):219-24
Long-term treatment with intracavernosal injections in diabetic men with erectile dysfunction.
Click here to access the PubMed abstract of this article.

Early intracavernosal injections following RP facilitated early sexual intercourse, patient satisfaction and potentially earlier return of natural erections.

Int J Impot Res. 2006 Feb 16
Early combination therapy: intracavernosal injections and sildenafil following radical prostatectomy increases sexual activity and the return of natural erections.
Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH,
Click here to access the PubMed abstract of this article.

More patients with ED and using ICI preferred it as their main treatment than was expected, even though they had a good response to oral sildenafil. A better quality of erection with ICI was the reason why experienced patients chose this method, differing from the choice of patients starting treatment for ED.

BJU Int. 2003 Aug;92(3):277-80
Preference for oral sildenafil or intracavernosal injection in patients with erectile dysfunction already using intracavernosal injection for > 1 year.
Department of Urology, College of Medicine, Chung-Ang University, Seoul, Korea.
Click here to access the PubMed abstract of this article.

17-alpha-hydroxyprogesterone caproate (17P)

17-alpha-hydroxyprogesterone caproate (17P) has been shown to decrease the rate of preterm birth in patients at increased risk.

Am J Obstet Gynecol. 2007 Mar;196(3):224.e1-4.
Increased recurrence of preterm delivery with early cessation of 17-alpha-hydroxyprogesterone caproate.
Department of Maternal Fetal Medicine, Mount Sinai School of Medicine, New York, NY
Click here to access the PubMed abstract of this article.

Obstetrics & Gynecology 2005;105:267-272
Estimated effect of 17 alpha-hydroxyprogesterone caproate on preterm birth in the United States.
National Office, March of Dimes, White Plains, New York.
Click here to access the PubMed abstract of this article.

Am J Obstet Gynecol. 2003 Feb;188(2):419-24.
Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study.
Obstetrics Clinic, University of Sao Paulo Medical School, Brazil
Click here to access the PubMed abstract of this article.

N Engl J Med 2003;348:2379-85
Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone Caproate
National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network
Click here to access the PubMed abstract of this article.

Drugs. 2004;64(21):2463-74
Progesterone treatment to prevent preterm birth.
Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, NC
Click here to access the PubMed abstract of this article.


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Ophthalmics

Examples of sterile ophthalmic drops, ointments, sprays, injections and pre-op solutions include anesthetics, antibiotics, antioxidants, antivirals, cataract therapies, corticosteroids, ophthalmic decongestants, miotics, lubricants, and macular degeneration and nutritional support formulas.

Examples of preservative-free preparations include drops or sprays containing the following medications, alone or in combination:

  • Cyclopentolate
  • Homatropine
  • Phenylephrine
  • Proparacaine
  • Scopolamine
  • Tetracaine
  • Tropicamide

Ask us about combinations to meet specific needs or medications that are currently unavailable or have been discontinued for non-safety reasons (such as when a newer therapy reduces the need and therefore decreased use results in the medication no longer being profitable to manufacturer).

Avastin Treatment

The Avastin treatment is a sterile compounding ophthalmic treatment. Avastinâ„¢ (bevacizumab) is being used by retinal specialists (as an off-label use) in the treatment of wet macular degeneration, or AMD. Wet AMD is a serious, vision-threatening condition. In wet AMD abnormal blood vessels behind the retina start to grow in the area of the retina known as the macula. These blood vessels leak blood and fluid causing damage to the macula and loss of vision. Studies have shown Avastinâ„¢ (bevacizumab) to benefit wet macular degeneration patients.


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Custom Prescription Dosage Forms

The Health Dimensions, Inc. pharmacists are problem solvers in the community, working with patients and physicians to gain positive outcomes. With our expertise in custom preparing medications, Health Dimensions, Inc. can compound any of the following dosage forms:

  • Capsules: immediate release or slow release
  • Drops: ear and nasal
  • Injectables: intravenous, subcutaneous, intra muscular, intra spinal
  • Nutritional and herbal therapies
  • Pellets
  • Sprays: nasal, inhalers, topical ear and oral
  • Suppositories: rectal and vaginal
  • Transdermals: cream, gel ointment, powder

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